N-乙酰-L-半胱氨酸

性状描述:

质量标准: 99%:


外观Appearance                          白色结晶或结晶粉末
红外光谱鉴别Infrared spectrometry       和对照品匹配
纯度Purity                              ≥99.0% (HPLC)
熔点Melting point                       108°C - 113°C
比旋光度Specific rotation [a]20/D       +4.5° ～ +6.5°(c=2, H2O)
水溶解试验Solubility in Water           溶液透明
灰分Ash                                
<0.5 % >

品级Grade                               细胞培养级  
                                   (for cell culture tested, ≥99.0% (HPLC))
外观Appearance                          白色至类白色粉末
红外光谱鉴别Infrared spectrometry       Conforms to standard
纯度Purity                              ≥99.0% (HPLC)
水溶解试验solubility in water           clear，colorless，100 mg plus 1 ml of water
水分water                                ≤3%(K.F)
细胞培养测试Cell culture test           pass



品级Grade                               药用级  
                                 (USP, EP, ≥98.5%)
appearance                              white crystalline powder
ir spectrum                             consistent with structure
Infrared spectrometry                   Conforms to standard
assay (dry basis) 98.5 to 101.0%
solubility in water                    0.5 G /10 ML in water, clear, colorless
Specific rotation [a]20/D               +21.3°～ +27.0°(C=5, Phosphate buffered saline)
zinc content                            ≤10 ppm
heavy metals                            ≤10 ppm
loss on drying                          ≤1.00%
residue on ignition                     ≤0.20%
l-cystine                               ≤0.5%
l-cysteine                              ≤0.5%
n,n＇diacetyl-l-cystine                  ≤0.5%
n,s-diacetyl-l- cysteine                ≤0.5%
other impurities                        ≤0.5% (each)
total impurities                        ≤0.5%
organic volatiles impurities            conforms by certification
ph test                                 2.0 to 2.8 (1g in 100ml water)
endotoxin assay                         ≤1 eu/mg
biochemical toxicity                    passes
note meets usp, ep requirements

储存条件: 密封保存

用途: 抗氧剂和粘多糖类试剂。有报道称能阻止神经细胞凋亡，但却诱发平滑肌细胞凋亡，阻止HIV复制。可能是微粒体谷胱甘肽转移酶的底物。